Disorders of The Nervous System

(4 Credits)

This course will address disorders of the nervous system, using examples selected from several of the the major classes of CNS disorders. The first lectures will address developmental disorders, followed by disorders of sensory systems. Subsequently there will be a series of topics that address neurological and psychiatric diseases with complex or heterogeneous etiology, such as schizophrenia and epilepsy. Neurodegenerative disorders and brain injury will(also be addressed. Finally, examples of cancer and infectious diseases that target the CNS will be presented. For each topic, a clinical overview will be provided, followed by research about underlying mechanisms, based on clinical research or animal models. The course will follow the textbook "Diseases of the Nervous System" (S. Gilman, Ed.). The course instructors are research scientists who have expertise in neuroscience and translational research. The major(goals of the course will be to introduce clinical topics to graduate students in a context that complements basic neuroscience courses, and provides opportunities to expand their perspectives from basic science to clinically-related endpoints.