Sequential Methods in Clinical Trials

(3 Credits)

This course offers an in-depth exploration of sequential methods used in the design and analysis of clinical trials. In the first half of the semester, the students will be introduced to the fundamental aspects of clinical trials, including their justification, structure, and key concepts. The second half of the semester will focus on the statistical methodologies associated with clinical trials, particularly sequential analysis, sample size and power calculation, adaptive design, and interim monitoring.