Cellular Engineering

1 Course Unit

The biological cell is a complex machine and its function is at the root of all physiology and many pathologies. Recent advances in molecular and cell biology enable the redesign of cell function. This course aims to develop a quantitative understanding of cell function, and how we might go about changing cell function through intelligent redesign. The course covers topics ranging from receptor binding and endocytosis, cell adhesion and motility, cell function in the immune system, systems and synthetic biology, genetic knockdown and manipulation using CRISPR and gene therapy, and strategies for immunotherapy including chimeric antigen receptor therapy (carT). Fall Prerequisite: CHEM 1022 AND (MATH 2400 OR ENM 2400) AND (PHYS 0140 OR PHYS 0150) AND (PHYS 0141 OR PHYS 0151) AND BIOL 1121 AND (ENGR 1050 OR CIS 1200 OR CIS 1210) 1 Course Unit