Mechanisms of Disease

1 Course Unit

Primary concepts in this course introduce the fundamental principles of pathophysiology, including normal and abnormal embryological development. Pathophysiology and development are covered by major organ systems. Lectures and class exercises will review normal as well as abnormal physiology in all systems. The focus of the course will be on understanding the pathophysiology of human genetic diseases. The coursework serves as the background for understanding specific diseases as they present in clinical genetics and research that has led to improved therapy and treatment for patients. The class will be primarily lecture-based using case-based learning. Students will give formal presentations on the pathophysiology of specific disorders. Fall 1 Course Unit