Advanced Biochemistry

Undergraduate catalogue

Applies the principles of organic chemistry to biochemistry. Explores enzymology through the lenses of physical organic chemistry, bioinorganic chemistry, catalysis. Covers how proteins orchestrate the reactivity of functional groups, the range of cofactors employed to extend the scope and diversity of biocatalysis, enzymatic systems controlled by their kinetics, and how knowledge of enzyme reaction mechanisms enables modern drug design. Prerequisites: MOL 345/CHM 345. Two 90-minute lectures, one preceptorial.