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ENCH 323

Biological Chemistry

3.00 units · Undergraduate / professional

Winter 2026 · Dr Ross and Dr Capicciotti

Topics

  • Biomolecules
  • amino acids and peptide bonds
  • protein structure and synthesis
  • enzyme kinetics, inhibition and catalysis
  • nucleic acids
  • carbohydrates
  • membranes
  • cell signalling
  • biosynthesis and metabolism.

Readings

  • No required textbook. Required lecture slides/notes supplied through onQ; supplemental lecture recordings posted after lectures.
Winter 2023 · Dr. Capicciotti

Topics

  • Learning
  • Reaction mechanisms
  • Synthesis
  • Proteins
  • Stereochemistry
  • Enzymes
  • Kinetics
  • Catalysis

Readings

  • Recommended: Biochemistry, Voet & Voet, 4th edition Note: older editions are also accepted (just make sure that there is no ambiguity on the assigned reading, either with your fellow students or with the instructor) Additional Useful Textbooks - Foundations of Chemical Biology, C.M. Dobson, J. A. Gerrard, A. J. Pratt, Oxford Chemistry Primers, Oxford University Press: this very short (92 pages) summarizes the essentials in an easy-to-read manner. This is an ebook available through the library. - Organic Chemistry, Clayden, Greeves & Warren: strong Organic Chemistry refresher Useful websites a) To read more: Encyclopedia of Biological Chemistry: http://www.sciencedirect.com/science/referenceworks/9780124437104. A collection of short review articles written by experts, A wonderful complement to the textbook! b) For research: - Web of Science (Access Through Databases Tab at http://library.queensu.ca/). Very helpful for finding journal articles by topic searching and for then finding other research that is related to those articles. - National Center for Biotechnology Information (NCBI): https://www.ncbi.nlm.nih.gov/. For journal articles, protein sequences, DNA sequences, align protein sequences (BLAST), find protein structures and lots more - ExPASY Proteomics Server (also known as Swiss-Prot): http://ca.expasy.org/. This an annotated database dedicated to proteins, which also contains lots of useful online tools for protein sequence and structure analysis. A user-friendly protein structure viewer is available for download as well (http://ca.expasy.org/spdbv/). - Protein Data Bank: https://www.rcsb.org/.
Sources