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ENCH 411

Advanced Analytical Chemistry

3.00 units · Undergraduate / professional

Fall 2026

Topics

  • Advanced analytical instrumentation
  • calibration strategies
  • coupling to liquid chromatography
  • mass-spectrometer components and analyzers
  • isotope abundances and elemental composition
  • GC–MS and LC–MS
  • EI, chemical ionization, ESI and MALDI
  • ambient ionization
  • mass-spectrometry imaging.

Readings

  • Recommended: Daniel C. Harris and Charles A. Lucy, Quantitative Chemical Analysis, 11th edition, W. H. Freeman & Company; previous editions acceptable. Course slides, practice problems and past-exam answers are supplied through onQ.
Fall 2022

Topics

  • Chemical vaporization
  • Hyphenation to liquid chromatography
  • Mass spectrometry instrumentation (Weeks 7-8)
  • ICP spectrometry and mass spectrometry applications: Oral presentations (Weeks 11-12)
  • Analytical chemistry
  • Learning
  • Attention

Readings

  • Recommended: Quantitative Chemical Analysis, 9th Ed., Daniel C. Harris, Freeman & Company (or other editions)
Sources