Uncovering Disease Biomarkers by Proteomics and Microscopy

3 credits

This team taught class will cover the theoretical aspects of proteomics and confocal microscopy, used to discover and validate, respectively, disease biomarkers for diagnosing clinical conditions. Learning to conduct a critical analysis of research articles, based on the scientific method and our knowledge of the techniques, will be an overarching goal the class. For each of the two major topics, we will start from first principles, examine the key facets of the method, tackle sample problems, and then dive into the current literature for examples of how the two methods are used to establish and validate key biomarkers. ***Prerequisite: BIOC 321***