Methods in Structural Biology

2.0 credits

This a graduate level course that provides theoretical and practical instruction on X-ray crystallography of biological molecules. The main objective is to provide students with an advanced, working knowledge of the approach. Hands-on activities include the manipulation of crystals for freezing, data collection, molecular replacement phasing, and refinement of coordinates. The course is part of the Biophysics core curriculum and is offered for half of the spring semester. Instructor Permission required for enrollment of graduate students outside of the Biophysics program.