Introcell Mech & Mechbio

4.0 credits

This course will examine the mechanical properties of cells and the mechanotransduction processes of clinical and technological importance. Topics covered include the role of mechanotransducing biomolecules, models of cell mechanics, and the methods to measure mechanical properties of cells. This course will also introduce students to effects of internal / external mechanical stimuli on cellular processes which may lead to various human diseases. Students will learn basic terminology and concepts of mechanics at the molecular and cellular level with an emphasis on quantitative analysis, modeling, and applications to clinical medicine. Two additional laboratory modules will provide hands-on experience to measure cellular mechanical properties and mechanotransduction signaling using FRET-based force sensors and Calcium dye.