The Design and Analysis of Clinical Trials

3 credits

Ethical considerations, intention-to-treat versus efficacy trials, principles of sampling and exclusion, methods of allocation and techniques of randomization, parallel versus cross over design, monitoring treatment outcomes, adverse effects, stopping rules, analytic techniques and data interpretation, and logistical issues in the management of clinical trials. Prerequisite: One of SPPH_V 502, SPPH_V 513. This course is not eligible for Credit/D/Fail grading.