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NPB 119

— Physiology of Aging & Senescence

(3 units)

Molecular and genetic basis of aging and senescence in various model organisms, from yeast to mammals. Organ and system level changes that take place as organisms age and their impact on their fitness and outcomes. The role of inflammation as a key contributor to aging. Mechanisms of common diseases of aging including: Alzheimer's, arthritis, atherosclerosis, osteoporosis. Theories of Aging. Ageism in modern society. Course is based on reading and evaluating primary literature.

Prerequisites & course information

Course Description: Molecular and genetic basis of aging and senescence in various model organisms, from yeast to mammals. Organ and system level changes that take place as organisms age and their impact on their fitness and outcomes. The role of inflammation as a key contributor to aging. Mechanisms of common diseases of aging including: Alzheimer's, arthritis, atherosclerosis, osteoporosis. Theories of Aging. Ageism in modern society. Course is based on reading and evaluating primary literature. Learning Activities: Lecture 3 hour(s). Grade Mode: Letter. General Education: Science & Engineering (SE). Learning Activities: Lecture 3 hour(s). Grade Mode: Letter. General Education: Science & Engineering (SE).

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