Introduction to X-ray Crystallography

4 credits

(Conjoined with CHEM 204.) Analysis of macromolecular structures by X-ray diffraction. Topics include symmetry, geometry of diffraction, detection of diffraction, intensity of diffracted waves, phase problem and its solution, heavy atom method, isomorphous replacement, anomalous dispersion phasing methods (MAD), direct methods, and molecular replacement. Prerequisites: PHYS 2A and 2B.