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CH 390L.2

Advanced Analytical Chemistry: Mass Spectrometry

3 Hours

Overview of the instrumentation, methods, and theory of mass spectrometry and gas-phase ion chemistry. Subjects include ionization methods, mass analyzers, vacuum components and pressure measurement, ion activation methods, analytical figures of merit, and integration of mass spectrometry with separation methods. Other subjects include gas-phase thermochemistry, kinetic theory of ion fragmentation, interpretation of mass spectra, and special subjects that may include ion mobility, proteomics, imaging, and elemental analysis, among others. Chemistry 390L (Topic: Advanced Analytical Chemistry: Mass Spectrometry) and 390L (Topic 2) may not both be counted.

Prerequisites & course information

Overview of the instrumentation, methods, and theory of mass spectrometry and gas-phase ion chemistry. Subjects include ionization methods, mass analyzers, vacuum components and pressure measurement, ion activation methods, analytical figures of merit, and integration of mass spectrometry with separation methods. Other subjects include gas-phase thermochemistry, kinetic theory of ion fragmentation, interpretation of mass spectra, and special subjects that may include ion mobility, proteomics, imaging, and elemental analysis, among others. Chemistry 390L (Topic: Advanced Analytical Chemistry: Mass Spectrometry) and 390L (Topic 2) may not both be counted.

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