Quantitative and Population Genetics

3 Hours

Discuss critical reading of primary quantitative literature on the drivers of genetic variation and its mapping to trait variation, focusing on humans. Analyze central ideas in mathematical modeling and statistical analysis of human genetic variation and explore areas from evolutionary genetics and medical genetics including mutation and recombination, genetic drift, natural selection, analyses of gene-expression variation, population structure, genotype-phenotype stratification, and study designs for mapping genotype to phenotype. Only one of the following may be counted: Biology 384K (Topic: Quantitative/Pop Genetics), Ecology, Evolution, and Behavior 384K (Topic: Quant/Population Genetics), 384K (Topic 2).