Biostatistics in Genetic Counseling

2 credits

Introduction to statistical methods used to evaluate probability of a condition or carrier status with genetic data, integrating pedigrees, genetics principles, and probability. Students evaluate literature relevant to genetic counseling and genotype-phenotype relationships. Includes overview of probability, odds ratios and recurrence risk, penetrance and expressivity, Bayes' Theorem, kinship estimation, linkage analysis and association testing. Prerequisite: GCNSL 515. Offered: W.