Principles of Precision Medicine

2 credits

Variation in drug absorption, distribution, elimination, and response, with emphasis on pharmacokinetic-pharmacodynamic relationships. Includes pharmacogenetics, drug-drug interactions, as well as ontogenic and disease state effects and associated precision testing platforms. Uses case studies to integrate possible sources of variation and impact on individual therapeutic decisions. Prerequisite: either MEDCH 501; PCEUT 531; and PCEUT 532, or permission of instructor; recommended: basic understanding of pharmacokinetics and principles of drug absorption, distribution and elimination and drug response. Offered: Sp.