Statistical Genetics III: Design and Analysis

3 credits

Overview of probability models, inheritance models, penetrance. Association and linkage. The lod score method. Affected sib method. Fitting complex inheritance models. Design mapping studies; multipoint, disequilibrium, and fine-scale mapping. Ascertainment. Prerequisite: STAT/BIOST 551; GENOME 371; or permission of instructor. Offered: jointly with BIOST 552; W.