Behavioral Genetics Laboratory

3 units

This course introduces students to fundamental concepts about how genes govern behavior by using the model system Drosophila melanogaster. Students learn modern and classic laboratory techniques including fly crossing, genetic screens, and behavioral assays. Specifically, we use the UAS/Gal4 system to drive cell-specific RNAi to investigate the role of ion channels in stress-induced generalized seizures. A primary goal of the course is to develop real-world research skills by having students design, propose, and execute a set of novel research questions. Statistical analysis and interpretation of data collected by the students are emphasized. To build a solid conceptual background, lectures are given once per week, and students read, analyze, and discuss primary research articles. Understanding is assessed through journal club assignments and presentations, research reports, and a final presentation of experimental results. Please do not submit override requests to the instructor. Contact Erin Gerrity (gerrity@wustl.edu) to be added to the waitlist. Students will be enrolled by the department from this outside waitlist.