Skeletal Muscle Pathophysiology

Graduate

Skeletal muscle not only produces the contractile force required for locomotion, breathing, and communication but is also indispensable for its roles in metabolism and as an endocrine, autocrine and paracrine organ. Skeletal muscle is highly responsive to a spectrum of exercise training modes, but unfortunately, this sensitivity extends to pathological situations. In this course, we will examine the pathophysiology of skeletal muscle in response to disease states such as diabetes, cancer, dystrophy, as well as aging, overtraining, traumatic injury, and disrupted circadian rhythms. The efficacy of exercise intervention to rescue skeletal muscle health will also be examined