ENGINEERING EXTRACELLULAR MATRICES
Overview of the structure, function and biophysical properties of extracellular matrix (ECM) proteins, followed by discussion of how control or manipulation of ECM protein expression and distribution impacts on cell and tissue function, concluding with impacts of engineering ECM for regenerative medicine.
Prerequisites & course information
Requisites: B M E 430 , graduate/professional standing, or member of Engineering Guest Students (or PHM SCI 430 prior to Fall 2026) Course Designation: Grad 50% - Counts toward 50% graduate coursework requirement Repeatable for Credit: No Last Taught: Spring 2026 Learning Outcomes: 1. Describe the structure and function of individual ECM components and their relevance to physiological and pathophysiological processes Audience: Both Grad & Undergrad 2. Apply biological knowledge of the ECM to inform the manipulation, mimicking, or engineering of ECM-based systems Audience: Both Grad & Undergrad 3. Critically evaluate ECM engineering approaches Audience: Both Grad & Undergrad 4. Apply advanced knowledge of bioconjugate chemistry to design dynamic scaffold platforms Audience: Graduate Learning Outcomes: 1. Describe the structure and function of individual ECM components and their relevance to physiological and pathophysiological processes Audience: Both Grad & Undergrad 2. Apply biological knowledge of the ECM to inform the manipulation, mimicking, or engineering of ECM-based systems Audience: Both Grad & Undergrad 3. Critically evaluate ECM engineering approaches Audience: Both Grad & Undergrad 4. Apply advanced knowledge of bioconjugate chemistry to design dynamic scaffold platforms Audience: Graduate
Sources
- Course catalogue ↗2026-2027