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B M E 770

NANOTECHNOLOGY IN NEUROSCIENCE

2 credits.

Principles of micro- and nano-technology applied to neuroscience, including technological approaches applied to both in vitro and in vivo neurobiological experimentation and neurology. Fundamentals of recording and processing neural signals using nanoscale synthesis processes and technologies including nanostructured electrodes and their electrical, mechanical, and biochemical properties, active and passive 2D and 3D multielectrode arrays (MEAs), nanoscale transistors for subcellular recordings, nanoparticles, and nano-synthesized agents for recording and stimulating neural activity. Relevant theory of cell electrode coupling, electrophysiology, and neurochemical signaling. Knowledge of microfabrication technologies and biology [such as in B M E 550 ] recommended.

Prerequisites & course information

Requisites: Graduate/professional standing Course Designation: Grad 50% - Counts toward 50% graduate coursework requirement Repeatable for Credit: No Last Taught: Spring 2026 Learning Outcomes: 1. Evaluate nerve cell signaling and apply signal processing methods for analyzing neural signals Audience: Graduate 2. Create nanofabrication processes for designing nano-scale patterning neural recording devices Audience: Graduate 3. Analyze neuron-device interface and compute coupling using equivalent electrical circuit models Audience: Graduate 4. Evaluate chemical synthesis techniques for biocompatible device coating, cell patterning, and nanoparticle-based sensing Audience: Graduate Learning Outcomes: 1. Evaluate nerve cell signaling and apply signal processing methods for analyzing neural signals Audience: Graduate 2. Create nanofabrication processes for designing nano-scale patterning neural recording devices Audience: Graduate 3. Analyze neuron-device interface and compute coupling using equivalent electrical circuit models Audience: Graduate 4. Evaluate chemical synthesis techniques for biocompatible device coating, cell patterning, and nanoparticle-based sensing Audience: Graduate

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