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BIOCHEM 560

PRINCIPLES OF HUMAN DISEASE AND BIOTECHNOLOGY

2 credits.

Covers basic and applied biochemical principles related to human disease. Topics such as: cancer, including cell cycle regulation, oncogenes and tumor suppressors, and cellular metabolism; metabolic disorders, including cardiovascular disease, metabolic syndrome, and diabetes; biotechnology, including metabolomics, CRISPR-based genetic screens, and experimental models of human disease.

Prerequisites & course information

Requisites: BIOCHEM 501 , 507 , NUTRI SCI 510, or graduate/professional standing Course Designation: Core GenEd - Natural Science & Wellness Breadth - Biological Science Level - Advanced L&S Credit - L&S Liberal Arts and Science Grad 50% - Counts toward 50% graduate coursework requirement Repeatable for Credit: No Last Taught: Spring 2026 Learning Outcomes: 1. Critically evaluate and accurately describe findings from primary research publications. Audience: Both Grad & Undergrad 2. Analyze how genetic and cell cycle perturbations contribute to cancer progression. Audience: Both Grad & Undergrad 3. Identify how genetic and environmental factors impact altered cellular metabolism in cancer. Audience: Both Grad & Undergrad 4. Describe biochemical mechanisms that contribute to cardiovascular disease, metabolic syndrome, and diabetes. Audience: Both Grad & Undergrad 5. Explain biochemical techniques, engineering strategies, and state-of-the-art technologies used in biomedical research. Audience: Both Grad & Undergrad 6. Collaborate with peers in a small group. Audience: Both Grad & Undergrad 7. Apply knowledge of biochemical principles and biotechnology to solve research and disease treatment related problems. Audience: Both Grad & Undergrad 8. Execute written critical evaluation of primary research literature related to the molecular basis of human diseases and advances in biotechnology. Audience: Graduate Learning Outcomes: 1. Critically evaluate and accurately describe findings from primary research publications. Audience: Both Grad & Undergrad 2. Analyze how genetic and cell cycle perturbations contribute to cancer progression. Audience: Both Grad & Undergrad 3. Identify how genetic and environmental factors impact altered cellular metabolism in cancer. Audience: Both Grad & Undergrad 4. Describe biochemical mechanisms that contribute to cardiovascular disease, metabolic syndrome, and diabetes. Audience: Both Grad & Undergrad 5. Explain biochemical techniques, engineering strategies, and state-of-the-art technologies used in biomedical research. Audience: Both Grad & Undergrad 6. Collaborate with peers in a small group. Audience: Both Grad & Undergrad 7. Apply knowledge of biochemical principles and biotechnology to solve research and disease treatment related problems. Audience: Both Grad & Undergrad 8. Execute written critical evaluation of primary research literature related to the molecular basis of human diseases and advances in biotechnology. Audience: Graduate

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