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BIOCHEM 620

EUKARYOTIC MOLECULAR BIOLOGY

3 credits.

Focuses on the basic molecular mechanisms that regulate DNA, RNA, and protein metabolism in eukaryotic organisms.

Prerequisites & course information

Requisites: BIOCHEM 501 , 508 or graduate/professional standing Course Designation: Core GenEd - Natural Science & Wellness + Lab Level - Intermediate L&S Credit - L&S Liberal Arts and Science Grad 50% - Counts toward 50% graduate coursework requirement Repeatable for Credit: No Last Taught: Spring 2026 Learning Outcomes: 1. Recall core principles that govern the structure and function of DNA, RNA, and protein. Audience: Both Grad & Undergrad 2. Describe techniques for quantifying the expression, interaction, and cellular localization of specific molecules and for determining their necessity and sufficiency in molecular processes. Audience: Both Grad & Undergrad 3. Explain how molecular processes that control the synthesis, decay, interactions, localization, folding, and modification of molecules are silenced, initiated, maintained, and terminated. Audience: Both Grad & Undergrad 4. Describe how information is transferred between molecules to alter cellular activity in response to developmental and environmental signals. Audience: Both Grad & Undergrad 5. Critique and weigh the credibility of existing molecular data. Audience: Both Grad & Undergrad 6. Develop and draw hypotheses that use existing data to account for as yet unexplained molecular processes in eukaryotic organisms. Audience: Both Grad & Undergrad 7. Design discovery/observation, loss-of-function, and gain-of-function experiments to test molecular hypotheses. Audience: Both Grad & Undergrad 8. Implement problem solving strategies in thesis research project. Audience: Graduate Learning Outcomes: 1. Recall core principles that govern the structure and function of DNA, RNA, and protein. Audience: Both Grad & Undergrad 2. Describe techniques for quantifying the expression, interaction, and cellular localization of specific molecules and for determining their necessity and sufficiency in molecular processes. Audience: Both Grad & Undergrad 3. Explain how molecular processes that control the synthesis, decay, interactions, localization, folding, and modification of molecules are silenced, initiated, maintained, and terminated. Audience: Both Grad & Undergrad 4. Describe how information is transferred between molecules to alter cellular activity in response to developmental and environmental signals. Audience: Both Grad & Undergrad 5. Critique and weigh the credibility of existing molecular data. Audience: Both Grad & Undergrad 6. Develop and draw hypotheses that use existing data to account for as yet unexplained molecular processes in eukaryotic organisms. Audience: Both Grad & Undergrad 7. Design discovery/observation, loss-of-function, and gain-of-function experiments to test molecular hypotheses. Audience: Both Grad & Undergrad 8. Implement problem solving strategies in thesis research project. Audience: Graduate

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