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BIOMDSCI 820

EARLY DRUG DISCOVERY

4 credits.

Examine the early drug discovery process, including target identification and validation, generation of diverse chemical libraries, assay development and high throughput screening, lead optimization by compound profiling, and drug targeting and delivery.

Prerequisites & course information

Requisites: Declared in Biotechnology MS Course Designation: Grad 50% - Counts toward 50% graduate coursework requirement Repeatable for Credit: No Last Taught: Fall 2026 Learning Outcomes: 1. Assess the early drug discovery process and key steps, from target identification to nonclinical trials. Audience: Graduate 2. Determine the scientific mechanism of one or more disease processes and assess how modulation of that target could treat or prevent a disease. Audience: Graduate 3. Compare current and emerging methods for generating compound diversity in chemical libraries, natural products, and antibodies, including molecular modeling and structure-based drug design. Audience: Graduate 4. Evaluate a technology used in drug discovery, understand the unmet need it addresses, and summarize the key information in a clear and concise way, both verbally and in a written format. Audience: Graduate Learning Outcomes: 1. Assess the early drug discovery process and key steps, from target identification to nonclinical trials. Audience: Graduate 2. Determine the scientific mechanism of one or more disease processes and assess how modulation of that target could treat or prevent a disease. Audience: Graduate 3. Compare current and emerging methods for generating compound diversity in chemical libraries, natural products, and antibodies, including molecular modeling and structure-based drug design. Audience: Graduate 4. Evaluate a technology used in drug discovery, understand the unmet need it addresses, and summarize the key information in a clear and concise way, both verbally and in a written format. Audience: Graduate

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