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BIOMDSCI 823

MOLECULAR TECHNOLOGIES III: ASSAY DEVELOPMENT

2 credits.

Evaluate laboratory assays and methods used in primary, secondary, and in vitro ADMETox (Absorption, Distribution, Metabolism, Excretion, Toxicity) drug screening. Build scientific communication and critical thinking skills while working on team projects and analyzing scientific results.

Prerequisites & course information

Requisites: Declared in Biotechnology MS Course Designation: Grad 50% - Counts toward 50% graduate coursework requirement Repeatable for Credit: No Last Taught: Fall 2026 Learning Outcomes: 1. Employ effective scientific communication methods demonstrating knowledge and skills when: writing scientific papers, preparing detailed scientific protocols, critiquing scientific journal articles in drug discovery, and developing and presenting detailed scientific presentations. Audience: Graduate 2. Determine how protein kinase and cytochrome P450 enzyme assay technologies are used in the drug discovery process. Audience: Graduate 3. Perform and evaluate multiple assay formats (luminescent, fluorescent, colorimetric) including, but not limited to: Cytochrome P450 enzymes, kinase assay technologies, cell culture techniques, and genome editing and CRISPR/Cas-9. Audience: Graduate 4. Compare and contrast the roles that fluorescent microscopy, high content screening, and in vivo imaging play in the drug discovery process and biotechnology. Audience: Graduate 5. Analyze and interpret scientific data and quality control measures as they relate to biotechnology and drug discovery, facilitating critical thinking. Audience: Graduate Learning Outcomes: 1. Employ effective scientific communication methods demonstrating knowledge and skills when: writing scientific papers, preparing detailed scientific protocols, critiquing scientific journal articles in drug discovery, and developing and presenting detailed scientific presentations. Audience: Graduate 2. Determine how protein kinase and cytochrome P450 enzyme assay technologies are used in the drug discovery process. Audience: Graduate 3. Perform and evaluate multiple assay formats (luminescent, fluorescent, colorimetric) including, but not limited to: Cytochrome P450 enzymes, kinase assay technologies, cell culture techniques, and genome editing and CRISPR/Cas-9. Audience: Graduate 4. Compare and contrast the roles that fluorescent microscopy, high content screening, and in vivo imaging play in the drug discovery process and biotechnology. Audience: Graduate 5. Analyze and interpret scientific data and quality control measures as they relate to biotechnology and drug discovery, facilitating critical thinking. Audience: Graduate

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