CLINICAL CASES IN MEDICAL GENETICS
The use of genetics in medicine has experienced significant growth over the past 50 years, identifying risk genes, and devising diagnostic tests and therapies based on this knowledge for specific clinical disorders such as cystic fibrosis, achondroplasia, and Retts syndrome. MDs and biomedical scientists from UW Hospital and Clinics, the School of Medicine and Public Health, and other UW units will present lectures in this field followed by question-answers sessions. Other class sessions will be devoted to student presentations and open discussion of research literature.
Prerequisites & course information
Requisites: GENETICS 466 , 467 or BIOCORE 383 Course Designation: Grad 50% - Counts toward 50% graduate coursework requirement Repeatable for Credit: No Last Taught: Spring 2026 Learning Outcomes: 1. Design experiments to discover the genes and defects within genes that cause diseases in humans Audience: Undergraduate 2. Understand how model organisms are used to investigate the molecular mechanisms for genetic disorders Audience: Undergraduate 3. Design and interpret diagnostic DNA-based tests for the detection of allelic variants that cause disease Audience: Undergraduate 4. Know the diverse physiological-developmental mechanisms that underlie a broad spectrum of diseases Audience: Undergraduate 5. Devise strategies to develop therapies to treat or cure disease and understand the limits therapeutic interventions Audience: Undergraduate 6. Develop a report on (1) the design of a diagnostic test for a genetic disorder, (2) the molecular biological pathways affected by the genetic disorder, and (3) application of the understanding of the disorder to develop a therapy or management regime Audience: Graduate Learning Outcomes: 1. Design experiments to discover the genes and defects within genes that cause diseases in humans Audience: Undergraduate 2. Understand how model organisms are used to investigate the molecular mechanisms for genetic disorders Audience: Undergraduate 3. Design and interpret diagnostic DNA-based tests for the detection of allelic variants that cause disease Audience: Undergraduate 4. Know the diverse physiological-developmental mechanisms that underlie a broad spectrum of diseases Audience: Undergraduate 5. Devise strategies to develop therapies to treat or cure disease and understand the limits therapeutic interventions Audience: Undergraduate 6. Develop a report on (1) the design of a diagnostic test for a genetic disorder, (2) the molecular biological pathways affected by the genetic disorder, and (3) application of the understanding of the disorder to develop a therapy or management regime Audience: Graduate
Sources
- Course catalogue ↗2026-2027