INVADERS AND DEFENSE

9 credits.

Integrated examination of how the immune system interacts with foreign microbes, the normal micro biome, and self tissues, both normal and malignant. Examines inflammation and the impacts of this type of response on normal cells, in wound healing, infectious disease, and inflammatory diseases including autoimmune disease and dermatologic conditions, including neoplasia of the skin. Covers the development of adaptive immune responses from vaccination, infectious processes, and organ transplantation. Covers the basic biology and pathophysiology of "invaders" of the human body, including viruses, fungi, and bacteria, along with their clinical diagnosis and therapy. Addresses malignant transformation of the immune effector cells themselves, including cancers of mature lymphoid cells and bone marrow derived malignancies.