BASIC SLEEP MECHANISMS AND SLEEP DISORDERS: FROM NEUROBIOLOGY TO SLEEP MEDICINE
Sleep occupies a third of our life, is found in all animal species carefully studied so far, and loss of sleep has both acute and long- term negative consequences on the brain and the body. Still, why we sleep remains unclear, and hypotheses on the role of sleep for synaptic homeostasis, learning and memory are being tested. Focuses on the neurobiology of sleep, with detailed review of the brain structures involved in controlling wake and sleep, as well as the circadian and homeostatic regulation of sleep. Other topics include changes in sleep need with age, animal models to study sleep, sleep disorders, and genetics of sleep.
Topics
- changes in sleep need with age
- animal models to study sleep
- sleep disorders
- and genetics of sleep
Topics explicitly listed in official catalogue description
Prerequisites & course information
Requisites: PSYCH 454 and ZOOLOGY/PSYCH 523 or graduate/professional standing Course Designation: Core GenEd - Natural Science & Wellness Level - Advanced L&S Credit - L&S Liberal Arts and Science Grad 50% - Counts toward 50% graduate coursework requirement Repeatable for Credit: No Last Taught: Fall 2026 Learning Outcomes: 1. Outline the physiology and definitions used to define sleep and wake Audience: Both Grad & Undergrad 2. Detail the brain structures and systems involved in the control of sleep and wake Audience: Both Grad & Undergrad 3. Describe circadian and homeostatic regulation of sleep and wakefulness Audience: Both Grad & Undergrad 4. Describe recent evidence linking sleep, memory, and synaptic plasticity Audience: Both Grad & Undergrad 5. Describe animal models used to study sleep Audience: Both Grad & Undergrad 6. Describe molecular and genetic approaches to the study of sleep Audience: Both Grad & Undergrad 7. Recognize how sleep changes across the lifespan Audience: Both Grad & Undergrad 8. Explain how sleep affects endocrine, metabolic, and cognitive functions Audience: Both Grad & Undergrad 9. Outline the importance of sleep for the individual and society, including negative consequences of sleep deprivation and sleep disorders Audience: Both Grad & Undergrad 10. List the symptoms, pathological mechanisms, epidemiology, and treatments of sleep disorders (including insomnia, sleep apnea, central nervous system hypersomnias, circadian rhythm disorders, parasomnias, and sleep-related movement disorders) Audience: Both Grad & Undergrad 11. Discuss additional very recent studies on sleep topics and learn how to recognize strengths and limitations of these studies relative to prior knowledge on sleep research Audience: Graduate 12. Describe how to design a sleep experiment and recognize the many confounding factors often associated with sleep studies Audience: Graduate Learning Outcomes: 1. Outline the physiology and definitions used to define sleep and wake Audience: Both Grad & Undergrad 2. Detail the brain structures and systems involved in the control of sleep and wake Audience: Both Grad & Undergrad 3. Describe circadian and homeostatic regulation of sleep and wakefulness Audience: Both Grad & Undergrad 4. Describe recent evidence linking sleep, memory, and synaptic plasticity Audience: Both Grad & Undergrad 5. Describe animal models used to study sleep Audience: Both Grad & Undergrad 6. Describe molecular and genetic approaches to the study of sleep Audience: Both Grad & Undergrad 7. Recognize how sleep changes across the lifespan Audience: Both Grad & Undergrad 8. Explain how sleep affects endocrine, metabolic, and cognitive functions Audience: Both Grad & Undergrad 9. Outline the importance of sleep for the individual and society, including negative consequences of sleep deprivation and sleep disorders Audience: Both Grad & Undergrad 10. List the symptoms, pathological mechanisms, epidemiology, and treatments of sleep disorders (including insomnia, sleep apnea, central nervous system hypersomnias, circadian rhythm disorders, parasomnias, and sleep-related movement disorders) Audience: Both Grad & Undergrad 11. Discuss additional very recent studies on sleep topics and learn how to recognize strengths and limitations of these studies relative to prior knowledge on sleep research Audience: Graduate 12. Describe how to design a sleep experiment and recognize the many confounding factors often associated with sleep studies Audience: Graduate
Sources
- Course catalogue ↗2026-2027