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PATH 752

CELLULAR AND MOLECULAR BIOLOGY/PATHOLOGY SEMINAR

1 credit.

The emphasis is on our current understanding of molecular and cellular mechanisms. Wherever possible, human diseases are used to illustrate the outcome at the organismal level of defects in these mechanisms. Discussions focus on immunology and cancer biology. Topics include mechanisms of cell survival, cell division, signal transduction, gene expression, vesicular transport, autophagy and cell death. Explore a broad set of cell biology topics, in greater detail such that they will have a better understanding of the breadth and diversity of cellular functions by the end of the semester. Learn how to critically evaluate the literature and the rigor of research.

Topics

Topics explicitly listed in official catalogue description

Prerequisites & course information

Requisites: Concurrent enrollment in PATH 750 Course Designation: Grad 50% - Counts toward 50% graduate coursework requirement Repeatable for Credit: No Last Taught: Spring 2026 Learning Outcomes: 1. Explain basic mechanisms of cell signaling Audience: Graduate 2. Describe how vesicles traffic inside of cells Audience: Graduate 3. Explain the parts of the cell cycle Audience: Graduate 4. Explain how and why a cell dies by apoptosis Audience: Graduate 5. Define cell adhesion receptors, lipid rafts, and phosphatases and explain their role in cellular mobility Audience: Graduate 6. Explain the role of stem cells in cancer biology Audience: Graduate 7. Describe B and T cell development pathways and the functions of these cells Audience: Graduate 8. Describe the roles of B and T cells in defending a host from pathogens Audience: Graduate 9. Learn how to critically evaluate papers for rigor Audience: Graduate 10. Learn how to design an experiment Audience: Graduate Learning Outcomes: 1. Explain basic mechanisms of cell signaling Audience: Graduate 2. Describe how vesicles traffic inside of cells Audience: Graduate 3. Explain the parts of the cell cycle Audience: Graduate 4. Explain how and why a cell dies by apoptosis Audience: Graduate 5. Define cell adhesion receptors, lipid rafts, and phosphatases and explain their role in cellular mobility Audience: Graduate 6. Explain the role of stem cells in cancer biology Audience: Graduate 7. Describe B and T cell development pathways and the functions of these cells Audience: Graduate 8. Describe the roles of B and T cells in defending a host from pathogens Audience: Graduate 9. Learn how to critically evaluate papers for rigor Audience: Graduate 10. Learn how to design an experiment Audience: Graduate

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