PHARMACOKINETICS
Introduction to pharmacokinetics. Fundamental principles and specific physical models are discussed. Absorption, distribution, metabolism, and excretion are thoroughly described including applications to pharmacotherapy mostly through a one body compartment model. Biopharmaceuticals and small molecule drugs are discussed based on their specific pharmacokinetics. All pharmacokinetics and pharmacodynamics principles and concepts are further described in depth in terms of their clinical applications with an emphasis on the role of the pharmacy professional.
Prerequisites & course information
Requisites: Declared in the Doctor of Pharmacy program Course Designation: Grad 50% - Counts toward 50% graduate coursework requirement Repeatable for Credit: No Last Taught: Spring 2026 Learning Outcomes: 1. Apply the one-compartment pharmacokinetic model as it relates to the IV bolus dose, extravascular dose, constant rate regimens and multiple dose regimens. Audience: Graduate 2. Describe drug movement through membranes, drug absorption, distribution and elimination. Audience: Graduate 3. Explain enzyme kinetics, protein binding, and blood flow influences on a drug’s pharmacokinetics. Audience: Graduate 4. Describe integration of drug kinetics with physiology. Audience: Graduate 5. Discuss drug Pharmacodynamics and its relationship to drug pharmacokinetics. Audience: Graduate 6. Develop a drug dosing regimen for a medication in a patient with kidney or liver impairment using only the FDA-approved labeling (prescribing information) for a medication. Audience: Graduate 7. Apply pharmacokinetics and pharmacodynamics to drug regimen modifications based on therapeutic drug monitoring. Audience: Graduate Learning Outcomes: 1. Apply the one-compartment pharmacokinetic model as it relates to the IV bolus dose, extravascular dose, constant rate regimens and multiple dose regimens. Audience: Graduate 2. Describe drug movement through membranes, drug absorption, distribution and elimination. Audience: Graduate 3. Explain enzyme kinetics, protein binding, and blood flow influences on a drug’s pharmacokinetics. Audience: Graduate 4. Describe integration of drug kinetics with physiology. Audience: Graduate 5. Discuss drug Pharmacodynamics and its relationship to drug pharmacokinetics. Audience: Graduate 6. Develop a drug dosing regimen for a medication in a patient with kidney or liver impairment using only the FDA-approved labeling (prescribing information) for a medication. Audience: Graduate 7. Apply pharmacokinetics and pharmacodynamics to drug regimen modifications based on therapeutic drug monitoring. Audience: Graduate
Sources
- Course catalogue ↗2026-2027