MEDICINAL CHEMISTRY I
Basic concepts in the chemistry of small molecule medicinal products. Structure activity of cholinergic, adrenergic, serotonergic and dopaminergic agents, antidepressant, antianxiety drugs, opioids, and antihistamines. Overview of drug metabolism and the clinical effects of metabolic drug interactions and genetic variability in drug metabolism genes.
Prerequisites & course information
Requisites: PHM SCI 432 Repeatable for Credit: No Last Taught: Spring 2026 Learning Outcomes: 1. Identify drugs, their therapeutic use, and side effects based on drug name and structure Audience: Undergraduate 2. Use pharmacophoric drug models to predict potency, metabolism, or side effects Audience: Undergraduate 3. Apply mechanisms of drug/xenobiotic biotransformation to parent drugs Audience: Undergraduate 4. Explain factors affecting drug/xenobiotic metabolism in humans, including both environmental and genetic effects and the resulting clinical implications Audience: Undergraduate Learning Outcomes: 1. Identify drugs, their therapeutic use, and side effects based on drug name and structure Audience: Undergraduate 2. Use pharmacophoric drug models to predict potency, metabolism, or side effects Audience: Undergraduate 3. Apply mechanisms of drug/xenobiotic biotransformation to parent drugs Audience: Undergraduate 4. Explain factors affecting drug/xenobiotic metabolism in humans, including both environmental and genetic effects and the resulting clinical implications Audience: Undergraduate
Sources
- Course catalogue ↗2026-2027