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PHM SCI 773

MOLECULAR SOLIDS

2-3 credits.

Science and technology of molecular solid materials with applications in medicine, food, energetic materials, and organic electronics.

Prerequisites & course information

Requisites: Graduate/professional standing Course Designation: Grad 50% - Counts toward 50% graduate coursework requirement Repeatable for Credit: No Last Taught: Spring 2026 Learning Outcomes: 1. Identify the molecules in molecular solids, including the active pharmaceutical ingredients Audience: Graduate 2. Use molecular structures to predict solid-state properties Audience: Graduate 3. Solve crystal structures and use the information to predict the properties of crystals Audience: Graduate 4. Describe the elemental steps of crystallization and their distinct kinetics and use the information to control a crystallization process Audience: Graduate 5. Identify, discover and predict crystal polymorphs and predict the effect of polymorphism on material properties, including dissolution and bioavailability Audience: Graduate 6. Predict aqueous solubility and its dependence on pH, complexing agents, common ions, and solid forms, and understand its impact on drug performance Audience: Graduate 7. Prevent crystallization and prepare amorphous solids and glasses and describe areas of applications where amorphous materials outperform crystalline materials Audience: Graduate 8. Design strategies to stabilize molecular solid materials against physical and chemical changes Audience: Graduate Learning Outcomes: 1. Identify the molecules in molecular solids, including the active pharmaceutical ingredients Audience: Graduate 2. Use molecular structures to predict solid-state properties Audience: Graduate 3. Solve crystal structures and use the information to predict the properties of crystals Audience: Graduate 4. Describe the elemental steps of crystallization and their distinct kinetics and use the information to control a crystallization process Audience: Graduate 5. Identify, discover and predict crystal polymorphs and predict the effect of polymorphism on material properties, including dissolution and bioavailability Audience: Graduate 6. Predict aqueous solubility and its dependence on pH, complexing agents, common ions, and solid forms, and understand its impact on drug performance Audience: Graduate 7. Prevent crystallization and prepare amorphous solids and glasses and describe areas of applications where amorphous materials outperform crystalline materials Audience: Graduate 8. Design strategies to stabilize molecular solid materials against physical and chemical changes Audience: Graduate

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