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PHMCOL-M 781

MOLECULAR AND CELLULAR PRINCIPLES IN PHARMACOLOGY

4 credits.

Provides an in-depth introduction to the molecular and cellular principles of pharmacology. Emphasis is on the mechanisms of drug and small molecule action in cells, with a particular focus on downstream signaling pathways, second messenger systems, protein kinase cascades, and the regulation of gene transcription.

Prerequisites & course information

Requisites: Graduate/professional standing Course Designation: Grad 50% - Counts toward 50% graduate coursework requirement Repeatable for Credit: No Last Taught: Spring 2026 Learning Outcomes: 1. Recognize the fundamental principles of drug actions at their target sites (e.g. receptors, enzymes, etc) Audience: Graduate 2. Understand the various mechanisms by which drugs can mediate their pharmacological effect Audience: Graduate 3. Describe how drugs mimic or modify physiological function, including the various actions and clinical uses Audience: Graduate 4. Describe the major classes of therapeutic drugs that affect the primary systems within the body Audience: Graduate 5. Choose a relevant experimental system to test experimental hypotheses (e.g. in vitro or in vivo; animal species, etc) Audience: Graduate 6. Design experiments which are properly controlled and which use appropriate statistical methods of data analysis Audience: Graduate Learning Outcomes: 1. Recognize the fundamental principles of drug actions at their target sites (e.g. receptors, enzymes, etc) Audience: Graduate 2. Understand the various mechanisms by which drugs can mediate their pharmacological effect Audience: Graduate 3. Describe how drugs mimic or modify physiological function, including the various actions and clinical uses Audience: Graduate 4. Describe the major classes of therapeutic drugs that affect the primary systems within the body Audience: Graduate 5. Choose a relevant experimental system to test experimental hypotheses (e.g. in vitro or in vivo; animal species, etc) Audience: Graduate 6. Design experiments which are properly controlled and which use appropriate statistical methods of data analysis Audience: Graduate

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