Immunobiology Seminar: B Cells in Immunity and Disease

Graduate / Professional

This is a limited-enrollment graduate seminar course that can serve as a required seminar course for immunobiology graduate students. Students for whom this course does not fulfill a course requirement may not be allowed to enroll. This course explores B cells in immunity and disease, including in autoimmunity and malignant transformation. A central goal of the course is for students to be able to use the knowledge gained to identify critical unanswered questions in the field. The emphasis is on fundamental aspects of B cell development and tolerance, maturation, and function, and dysregulation in disease and upon addressing unanswered questions in the field. Assigned readings include review articles and papers from the primary literature, but students are expected to identify additional readings from the literature as they develop their ideas. Each class features two presentations by students on aspects of the topic of that week, as well as substantial input from other students. Student evaluation is based on class participation, oral presentations, and a short written grant, and its evaluation by student peer review. Prerequisites: IBIO 5300 , Biology of the Immune System. IBIO 5310 , Advanced Immunology, is recommended but not required. Enrollment limited to twenty, with preference given to students who require participation in IBIO seminars to complete their course requirements. TTh 2:35pm-3:50pm