SC/BIOL 4010
Biology of Cancer
Winter 2026
Topics
- Tumour development
- cancer hallmarks
- oncogenes
- tyrosine kinases and Ras
- tumour suppressors
- pRb, BRCA, APC and p53
- viral oncogenesis
- cancer genomics
- targeted treatment
Readings
- Required articles: Hanahan and Weinberg (2011), hallmarks of cancer, Cell 144:646–674; Blume-Jensen and Hunter (2001), Oncogenic kinase signaling; Munger et al. (2004), Mechanisms of Human Papillomavirus-Induced Oncogenesis; Vogelstein et al. (2013), Cancer Genome Landscapes; Hunter (2007), Treatment for chronic myelogenous leukemia: the long road to imatinib.
- Recommended: Weinberg, The Biology of Cancer, 2nd or 3rd ed.; Cancer Medicine, 6th ed.; Coffin, Hughes and Varmus, Retroviruses.
Sources
- Course catalogue ↗2026–2027
- Public course outline ↗Winter 2026